Posts Tagged ‘gi’

First multi-PI combined training program between CWRU and Cleveland Clinic headed by Fabio Cominelli

June 9, 2010
Beginning in July, the first multiple-principal investigator combined training program between Case Western Reserve University and Cleveland Clinic will be initiated by Fabio Cominelli MD, PhD, the Hermann Menges, Jr. Chair in Internal Medicine at the School of Medicine, and Claudio Fiocchi MD¸ Clifford and Jane Anthony Chair for Digestive Disease Research and Education, Lerner Research Institute at Cleveland Clinic.
The National Institute of Diabetes, Digestive and Kidney Diseases provided the new joint effort with a five-year grant worth nearly $1M. The funding supports post-doctoral fellows in obtaining digestive disease science training for a period of three years; for physicians this will be in conjunction with their clinical training in gastroenterology.
This training program is unique in that it follows the city-based program model of the Clinical and Translational Science Collaborative (CTSC). Trainees will come to Cleveland with the option to train either at the Lerner Research Institute or the School of Medicine, and they will have the ability to choose among 20 mentors whose laboratories are supported by more than $20 million per year in National Institutes of Health funding.

CWRUmedicine’s Inflammatory Bowel Disease Research Update

March 23, 2010

Investigators, led by Fabio Cominelli, M.D., Ph.D., formed an integrated team to explore multiple aspects of intestinal inflammation utilizing clinical resources as well as animal models of Crohn’s disease and ulcerative colitis. Some of the topics under investigation include intestinal cytokine regulation, immune-nonimmune cell interactions, extracellular matrix biology, tolerance to indigenous intestinal flora, and state-of-the-art gene expression profiling by DNA microaray technology. In collaboration with the Division of Pediatric Gastroenterology and Nutrition, these investigators have been previously awarded by the National Institutes of Health a large five-year program project grant to study pediatric inflammatory bowel disease, the only such program in the country during that period. Basic research is complemented by a variety of clinical and translational studies. These include investigation of inflammatory bowel disease in minority populations, intestinal permeability in Crohn’s disease families, and an active program of clinical trials with state-of-the-art immunomodulators and biologicals.

Learn more at CWRUmedicine.org