Posts Tagged ‘new cancer test’

Dr. Afshin Dowlati discusses a new way to predict effectiveness of chemotherapy

March 29, 2010

Doctors often have trouble knowing who might respond to certain cancer treatments. “We kind of give chemotherapy and wish for a good result,” says Dr. Afshin Dowlati. That could change.

Dowlati led a study that revealed lung cancer patients with low levels of a molecule that controls cellular interaction have twice the chance of responding to chemotherapy than those with high levels. Those levels can also predict how likely a patient is to live a year after diagnosis. The difference could help patients decide whether to try chemotherapy, drugs or pursue alternative therapies, Dowlati says.

Learn more at CWRUmedicine.org

New test developed by CWRUmedicine researchers may reduce colon cancer

March 7, 2010

Colon cancer is the second most deadly cancer in the U.S. despite being the most preventable. The American Gastroenterological Association (AGA) recently announced concern that people will neglect colon cancer screening during this economic climate.

Screening is recommended in both sexes over age 50 and earlier if a patient has a family history of this disease. However, some people put it off due to fear of having a colonoscopy, which can be both invasive and expensive. As more people lose health insurance coverage, the high cost of this procedure may lead many more people to forego screening.

Sanford Markowitz, MD, CWRUmedicine oncologist and colon cancer researcher of the University Hospitals Ireland Cancer Center at University Hospitals Case Medical Center, has developed a less expensive, non-invasive test for this disease.

About the test:

  • The non-invasive test detects DNA markers for colon cancer using a stool sample that is taken at home
  • The DNA Stool Test is available now at the doctor’s office, or can be easily ordered by the doctor
  • Although the test isn’t covered by insurance, the cost is significantly lower
  • Patients with negative results will not need to commit time and money to having a colonoscopy; patients with positive results will move forward with  colonoscopy to provide more information
  • It is 80 percent effective and while colonoscopy is still the most effective test, it is not useful if patients are avoiding it altogether
  • The American Cancer Society added the test to its screening guidelines last year

Learn more at CWRUmedicine.org